The software consists of two parts. A Python script for estimating the HMMs called tain_rank.py and the trainmet R-package which serves as an (optional) wrapper for train_rank.py and performs statistic summarization and visualization. To use it, first install all dependencies for train_rank.py as described in http://www.cin.ufpe.br/~igcf/Metabolites/scripts/hmm/readme.txt. Only Linux/MacOSX are supported. Then, install the trainmet R-package's dependencies Biobase and pls by starting R and calling #+begin_src R source("http://www.bioconductor.org/biocLite.R") biocLite("Biobase") install.packages("pls") #+end_src then, install trainmet by in a shell calling #+begin_src sh wget http://www.cin.ufpe.br/~igcf/Metabolites/scripts/trainmet_0.0.3.tar.gz R CMD INSTALL trainmet_0.0.3.tar.gz #+end_src for a brief demonstration of the package do: #+begin_src R library(trainmet) openVignette("trainmet") #+end_src